Three- dimensional molecular structure is one of the foundations of structure- based drug design Often, data are available for the shape of a protein and a drug separately, but not for the two together The program AutoDock was originally written in FORTRAN-77 in 1990 by David S Goodsell here in Arthur J Olson's laboratory It performs automated docking of ligands (small molecules like a candidate drug) to their macromolecular targets (usually proteins, sometimes DNA) [Garrett B Morris, "Molecular docking web", Scripps, Dec 2000] http: //www scripps edu/pub/olson-web/people/gmm/index html
Slitting a loaf with 1/4" - 1/2" cuts, for the purpose of guiding the bloom of the loaf so that it swells where the baker wants it to and for decorative purposes
Cutting and trimming the long hairs in a horse's tail or cutting off the tail of a sheep
The act of coupling two or more orbiting objects; the operation of mechanically connecting together, or in some manner bringing together, orbital payloads