(Medicine) hereditary disease characterized by anemia resulting from defective hemoglobin production (causes deformed red blood cells, oxygen deficiency, and circulatory problems)
A chronic, usually fatal anemia marked by sickle-shaped red blood cells, occurring almost exclusively in Black people of Africa or of African descent, and characterized by episodic pain in the joints, fever, leg ulcers, and jaundice. The disease occurs in individuals who are homozygous for a mutant hemoglobin gene. Also called sickle cell disease
sickle-cell anaemia in AM, use sickle-cell anemia Sickle-cell anaemia is an inherited illness in which the red blood cells become curved, causing a number of health problems. sickle-cell anemia a serious illness that mainly affects black people, in which the blood cells change shape, causing weakness and fever