reverse transcriptase

listen to the pronunciation of reverse transcriptase
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(Tıp) reverse transcriptase
Английский Язык - Английский Язык
A polymerase that catalyzes the formation of DNA from RNA; found in retroviruses
an enzyme that, in simple terms, changes viral RNA in to double stranded DNA enabling the viral genome to be integrated in to the host cell
An RNA-dependent DNA polymerase that catalyzes the synthesis of DNA from deoxyribonucleoside-5'-triphosphates, using RNA as a template The enzyme has been found in retroviruses & in some other viruses The reaction catalyzed by the enzyme is in contradiction to the flow of genetic information described by the original central dogma of molecular biology: DNA to RNA to Protein The enzyme actually has three enzymatic activities: (1) It copies a single-stranded RNA mole to yield a double-stranded DNA-RNA hybrid(2) It copies a single-stranded DNA mole to yield a double-stranded DNA mole (3) It degrades the RNA in DNA-RNA hybrid (this is called its ribonuclease H, RNAase H, activity)
This enzyme of the HIV virus (and other retroviruses) converts the single-stranded viral RNA into DNA, the form in which the cell carries its genes The antiviral drugs approved in the US for the treatment of HIV infection-AZT, ddC and ddI-all work by interfering with this stage of the viral life cycle See also AZT; ddC; ddI; DNA; Ribonucleic Acid
      A   viral  enzyme  that   copies  the  genetic  information  of  HIV   from  its
An enzyme, requiring a DNA primer, that catalyzes the synthesis of a DNA strand from an RNA template An enzyme that can use RNA as a template to synthesize DNA
a polymerase that catalyzes the formation of DNA using RNA as a template; found especially in retroviruses
An enzyme used by retroviruses to form a complementary DNA sequence (cDNA) from an RNA template -usually the genome of the retrovirus The enzyme then performs a complimentary template of the cDNA strand such that a double stranded DNA molecule is formed This double stranded DNA molecule is then inserted into the chromosome of the host cell which has been infected by the retrovirus Reverse transcriptase is one of the key components that HIV uses to mount its attack Source : PhRMA Genomics
an enzyme that catalyzes the formation of DNA using an RNA template, and is thus an RNA-dependent DNA polymerase The name refers to the fact that the enzyme transcribes nucleic acids in the reverse order from the usual DNA-to-RNA transcription
A polymerase that catalyzes the formation of DNA on an RNA template, found in oncogenic viruses containing RNA, especially the retroviruses
An enzyme used by retroviruses to form a complementary DNA sequence (cDNA) from their RNA The resulting DNA is then inserted into the chromosome of the host cell
an enzyme capable of copying RNA into DNA during the HIV replication cycle Several anti-HIV drugs -- such as AZT, ddI, ddC -- are chemicals that act against the reverse transcriptase enzyme
the enzyme produced by HIV and other retroviruses that enables them to direct a cell to synthesize DNA from their viral RNA
(RT): a viral enzyme that allows a retrovirus to translate its genetic material (in the form of RNA) into DNA, which is then integrated into the chromosomes of the host cell
An enzyme that catalyzes the synthesis of DNA from using RNA as a template
An enzyme in the core of a retrovirus enabling it to write its own genetic program into a host cell's DNA
An enzyme that copies RNA to DNA; a necessary feature of RNA viruses
A viral enzyme that constructs DNA from an RNA template, an essential step in building a retrovirus such as HIV

Связанные Термины

reverse transcriptase inhibitor
an antiviral drug that inhibits the action of reverse transcriptase in retroviruses such as HIV
non-nucleoside reverse transcriptase inhibitor
an antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs
nucleoside reverse transcriptase inhibitor
an antiviral drug used against HIV; is incorporated into the DNA of the virus and stops the building process; results in incomplete DNA that cannot create a new virus; often used in combination with other drugs
Турецкий язык - Английский Язык
(Tıp) reverse transcriptase
reverse transcriptase
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