haplotype

listen to the pronunciation of haplotype
Английский Язык - Турецкий язык
haplotip
Английский Язык - Английский Язык
To characterize with respect to haplotype
A group of alleles that are transmitted together
The nucleotides present at all of the known polymorphic sites in a gene; also a set of closely linked genes that are inherited together
A set of genes on a single chromosome
A set of closely linked genes that tends to be inherited together as a unit, as occurs with the A, B and C loci of the human leukocyte antigen (HLA) gene complex
One of the alternative forms of the genotype of a gene complex This term is applied to gene complexes rather than the term allele, which refers to one of the forms of a single gene See H2 for an example
a set of genes that determine different antigens but are closely enough linked to be inherited as a unit; the antigenic phenotype determined by a haplotype
A way of denoting the collective genotype of a number of closely linked loci on a chromosome Source : Human Genome Project Information
This is the tissue type contributed by either the mother or father to their offspring It is implied that it represents the genes on one set of parental chromosomes When a transplant procedure is between a donor and recipient who are haplotype identical, it means that the tissue type or HLA type of each is identical in respect to mother or father but not identical to the other In some situations, if the discrepancy is not too great the transplant may still be possible if the underlying disease makes the risk of partial compatibility warranted Conditioning of the recipient and lymphocyte depletion of the donor stem cell suspension are steps taken to mitigate the risk of immune cell activation by the tissue type differences
The linear, ordered arrangement of alleles on a chromosome Haplotype analysis is useful in identifying recombination events [Source: NHBLI/NCBI Glossary]
Pertaining to a particular set of alleles at linked loci (or nucleotide changes within a gene) that are found together on a single homolog In linkage studies with backcross offspring and RI strains, the haplotypes associated with each sample provide a means for determining the order of loci (see Chapter 9) See Haplotype in the MGI Glossary
A way of denoting the collective genotype of a number of closely linked loci on a chromosome
"Distinct Y chromosomes identified by STR's are designated as haplotypes Stated in another way: a haplotype is represented by the number of repeats at certain alleles, or markers on the y chromosome " (from Peter de Knijff)
a combination of alleles at two or more loci in a region of a chromosome
The results of the Y-chromosome test that can be used for DNA matching It can be a single or unique set of chromosomes Haplotypes are described by the number of base repeats (A, C, T or G) at the microsatellite loci (DYS) and in general are defined by "rapidly" mutating loci (cf haplogroup) The Extended European Haplotype is defined by loci DYS 19, 385 I/II, 389I, 389II, 390, 391, 392, 393, YCAII a/b A new 20-plex technique is being added for following loci: DYS 426, A7 1, H4, 388, 437, 438, 439, 447, 448, and more
haplotype

    Произношение

    Этимология

    [ 'ha-plO-"tIp ] (noun.) 1969. Blend of haploid and type.
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