penetrance

listen to the pronunciation of penetrance
İngilizce - Türkçe
(Tıp) etkililik
penetrans
(Tıp) Işının nüfuz yeteneği

İlgili Terimler

penetrance coefficient
girginlik ölçer
İngilizce - İngilizce
The proportion of individuals carrying a particular variation of a gene that also express an associated trait
The probability of a gene or genetic trait being expressed "Complete" penetrance means the gene or genes for a trait are expressed in all the population who have the genes "Incomplete" penetrance means the genetic trait is expressed in only part of the population The percent penetrance also may change with the age range of the population
The probability of expressing a phenotype given a genotype Penetrance is described as either "complete"or" incomplete "For example, individuals who carry the gene for tuberous sclerosis have an 80% chance of expressing the disorder Penetrance may also be dependent on a susceptible individual's current age For example, 20% of all gene carriers for myotonic dystrophy express the gene to some degree by age 15 while 80% of all gene carriers express it by age 60 Incomplete penetrance is usually a matter of chance or modifiers in the genetic background Source : PhRMA Genomics
The quality or state of being penetrant; power of entering or piercing; penetrating power of quality; as, the penetrancy of subtile effluvia
A term indicating the likelihood that a given gene will actually result in disease
Proportion of individuals possessing a genetic trait who manifest specific features of the trait
Pertaining to the failure of some animals with a mutant genotype to express the associated mutant phenotype In any case where less than 100% of genotypically mutant animals are phenotypically mutant, the phenotype is said to be "incompletely penetrant" Incomplete penetrance is usually a matter of chance or modifiers in the genetic background See Penetrance in the MGI Glossary
penetrance