the localized death of living cells (as from infection or the interruption of blood supply)
A term formerly restricted to mortification of the soft tissues which has not advanced so far as to produce complete loss of vitality; but now applied to mortification of the soft parts in any stage
The death of body tissue It is most often caused by a loss of blood flow, especially in the legs and feet
the death of tissue on a large scale May be caused by certain bacteria which spread rapidly through tissues, or by an inadequate blood supply
a death of body tissue that usually occurs when there has been an interruption of blood supply, followed by bacterial invasion
Gangrene is the decay that can occur in a part of a person's body if the blood stops flowing to it, for example as a result of illness or injury. Once gangrene has developed the tissue is dead. a condition in which your flesh decays in part of your body, because blood has stopped flowing there as a result of illness or injury (gangraena, from gangraina). Localized soft-tissue death (necrosis) from prolonged blood-supply blockage. It can occur in atherosclerosis, diabetes mellitus, or decubitus ulcer, and after severe burns or frostbite. In dry gangrene, gradual blood-supply decrease turns the part discoloured and cold, then dark and dry. Treatment requires improving blood flow. Moist gangrene comes from a sudden blood-supply cutoff. Bacterial infection causes swelling, discoloration, and then a foul smell. Along with antibiotics, tissue removal may be needed to prevent spread, which can be fatal. A more virulent form, gas gangrene, is named for gas bubbles under the skin produced by a highly lethal toxin from clostridium bacteria. The wound oozes brownish, smelly pus. Infection spreads rapidly, causing death. All dead and diseased tissue must be removed and antibiotics given; an antitoxin can also be used