yac

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Definition of yac in English English dictionary

Yeast Artificial Chromosome A vector for cloning very large genomic inserts of 300 kb to one megabase in length (see Chapter 10) See YAC in the MGI Glossary

Yeast Artificial Chromosome (see cloning vector) used to clone DNA fragments up to 1 Mb

Yeast artificial chromosome These cloning vectors were developed using yeast centromere and telomere sequences The average insert size of these clones ranges from 100-1000 Kb These clones can span large portions of the genome rapidly, but can be highly unstable Read more about YACs reference: Burke DT et al (1987) Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors Science 236(4803): 806-12