To be retired after three strikes (missed swings, as opposed to any other way of becoming "out.")
He struck out on a nasty slider.
To be refused a request or to have a proposal not be accepted, in particular a request for a (hopefully romantic) date
Dave asked the new girl out but he struck out.
To draw a line through some text such as a printed or written sentence, with the purpose of deleting that text from the rest of the document. The text so deleted may be completely obscured, or it may be deliberately left legible with the line through it so that readers can see that it was deliberately deleted
To strongly criticize or defend with words, in particular as a rebuttal to previous criticism
To lash out; to strike or hit at someone or something, particularly something in arm's length of the striker and at or near the level of the striker's head
Usually, getting all three strikes in the tenth frame; also sometimes the same as punch out
If someone strikes out, they fail. The lawyer admitted that he was the firm's second lawyer. The first one had struck out completely. see also strike 19
If you strike out at someone, you hit, attack, or speak angrily to them. He seemed always ready to strike out at anyone and for any cause Frampton struck out blindly, hitting not Waddington, but an elderly man
cause to retire; "The pitcher retired three batters"; "the runner was put out at third base"
be unsuccessful in an endeavor; "The candidate struck out with his health care plan
If you strike out, you begin to do something different, often because you want to become more independent. She wanted me to strike out on my own, buy a business. a desire to make changes and to strike out in new directions
put out or be put out by a strikeout; "Oral struck out three batters to close the inning"
To get all three available strike in the tenth frame or, similarly, finish the game from any point with strikes