talidomit

Turkish - English

Definition of talidomit in Turkish English dictionary

thalidomide

-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)dione — C13H10N2O4 — A drug that was sold during the late 1950s and 1960s as a sleeping aid, and to pregnant women as an antiemetic to combat morning sickness and other symptoms, but was withdrawn after being proven to cause severe birth defects, such as phocomelia; currently used to treat leprosy

{i} drug formerly used as a sedative but found to cause severe birth defects

A drug that reduces levels of TNF and inhibits angiogenesis It is being studied as a treatment for AIDS-related wasting, aphthous ulcers, diarrhea and Kaposi's sarcoma Potential side effects include sedation, constipation, peripheral neuropathy and severe birth defects in the infants born to women taking the drug during pregnancy Safer thalidomide analogs are under development that have less anti-angiogenesis activity but still greater TNF inhibitory potential

a sedative and hypnotic drug; withdrawn from sale after discovered to cause severe birth defects because it inhibits angiogenesis

Thalidomide is a drug which used to be given to pregnant women, before it was discovered that it resulted in babies being born with wrongly shaped arms and legs

A drug that was sold during the late 1950s and 1960s as a sleeping aid, and to pregnant women as an antiemetic to combat morning sickness and other symptoms, but was withdrawn because it causes severe birth defects

This drug seems to have an anti-angeogenesis (anti-tumour) effect It cuts off the blood supply to the myeloma cells and causes it to die Good response achieved in initial trials with few side effects, now in trials in the UK Too early to say how long the response lasts or if there are any long term problems

Thalidomide is used to describe someone whose arms and legs are wrongly shaped because their mother took thalidomide when she was pregnant. the special needs of thalidomide children. a drug given to people to make them calm, until it was discovered that it harmed the development of the arms and legs of unborn babies (phthalic acid type of acid (19-21 centuries) (from naphtha) + imide type of chemical compound (19-21 centuries) (from , from amide)). Drug formerly used as a sedative and to prevent morning sickness during pregnancy. Synthesized in 1954, it was introduced in almost 50 countries, including West Germany and Britain, where it became popular because it was effective and huge overdoses were not fatal. In 1961 it was found to cause congenital disorders; when it is taken in early pregnancy, some 20% of fetuses have phocomelia (defective development of the limbs) and other deformities; 5,000-10,000 such babies were born. It was never distributed for clinical use in the U.S. (see Helen Brooke Taussig). Thalidomide appears effective against inflammatory and autoimmune disorders, including certain late-stage AIDS symptoms, and is licensed for use in such treatments in some countries

a sedative drug under investigation for treatment of aphthous ulcers, wasting syndrome and other conditions in persons with HIV disease Thalidomide has been shown to reduce levels of tumor necrosis factor-alpha (TNF-alpha) in vitro The drug has teratogenic effects and may cause severe birth defects; other side effects include skin rashes and peripheral neuropathy

A drug to help morning sickness that was withdrawn in 1961 after it was found to cause limb deformities in babies born to women who had taken it

Drug used in the 50s and 60s to suppress the effects of morning sickness It caused Birth Defects similar to TAR Thalidomide Resources >>

tranquilizing drug that can have a teratogenic effect on the auditory system of the developing embryo when taken by the mother during pregnancy, resulting in congenital hearing loss

                        A medication  that  reduces   the  levels  of  TNF  (see)   It  is  used   as  a                                 primary  or  adjunctive   treatment  for  wasting  syndrome  and   aphthous                                 ulcers   (see)    The   most    common    side-effects      include    sedation,                                 fevers,  peripheral  neuropathy  (see)  and  severe  birth   defects   in  the                                 offspring of pregnant women

Hyphenation

ta·li·do·mit