randomized trial

English - English

Definition of randomized trial in English English dictionary: A clinical trial with at least two arms, in which the decision as to which arm a new patient is assigned is made by chance, for instance, by the flip of a coin, or by using a computer to select randomly A great myth about cancer clinical trials is that all trials are randomized This is not true, though most Phase III and Adjuvant Trials are; A study in which participants are randomly assigned to either a treatment arm or placebo arm of a clinical trial See also Clinical Trial; Placebo; an experiment arranged so as to produce a chance distribution of subjects into different treatment groups or arms; a study in which participants are assigned by chance to one of two or more intervention arms or regimens Randominization minimizes the differences among groups by equally distributing people with particular characteristics among all the trial arms; an experiment arranged to produce a chance distribution of subjects into different treatment or control arms Randomization is done to cancel out the influence of factors that are not under study With successful randomization, the chance of one individual being placed in a given study arm is independent of the placement of others, and the only differences between the groups are those intended by the experimenter (e g , different drugs taken); A study in which participants are assigned by chance to one of two or more intervention arms or regimens Randomization minimizes the differences among groups by equally distributing people with particular characteristics among all the trial arms