oncogenes

English - Turkish

Definition of oncogenes in English Turkish dictionary
oncogene: (Biyokimya) urkalıt

English - English

Definition of oncogenes in English English dictionary: Normal genes of vertebrates that are involved in control of cell growth and have been preserved throughout evolution When mutated, overexpressed, or amplified in somatic cells, oncogenes may cause neoplastic transformation; genes that normally play a role in the growth of cells but, when overexpressed or mutated, can foster the growth of cancer; Abnormal genes associated with tumors; genes that promote cell growth and duplication These genes are normally present in all cells But oncogenes may undergo changes (mutations) that activate them, causing cells to grow too quickly and form tumors; plural of oncogene; genes having the potential to cause a normal cell to become cancerous; Oncogenes are genes that promote proliferation of a cell, as opposed to tumor suppressor genes, which have the opposite effect However, they have one major difference from regular proliferation-promoting genes: they are mutated and so are always "on " They contribute to the development of cancer; Certain stretches of cellular DNA that, when activated, contribute to the malignant transformation of cells; any of a family of genes that normally code for proteins involved in cell growth or its regulation If mutated or activated by retroviruses, it may contribute to a malignancy
oncogene: Any gene that contributes to the conversion of a normal cell into a cancerous cell when mutated or expressed at high levels
oncogene: A gene thought to be capable of producing cancer
oncogene: The part of the cell that normally directs cell growth, but which can also promote or allow the uncontrolled growth of cancer if damaged (mutated) by an environmental exposure to carcinogens, or if damaged or missing because of an inherited defect A gene that has the potential to cause a normal cell to become cancerous
oncogene: A gene whose action promotes cell proliferation Oncogenes are altered forms of proto-oncogenes
oncogene: A gene which, functioning abnormally, encourages normal cells to turn cancerous
oncogene: A gene, one or more forms of which is associated with cancer Many oncogenes are involved, directly or indirectly, in controlling the rate of cell growth
oncogene: One or more genes that produce cancer These genes are normally repressed, but a variety of factors can cause their activation, including virus infections, carcinogenic chemicals, and nonionizing and ionizing radiation
oncogene: Gene thought to be capable of producing cancer
oncogene: A gene whose activity is associated with the conversion of normal cells to cancer cells (See 411)
oncogene: A gene coding for a protein that can contribute to the transformation of a normal cell into a tumor cell
oncogene: Any gene that contributes to the conversion of a normal cell into a cancerous cell
oncogene: A type of gene that is normally inactive When these genes are "turned on" (activated), they cause normal cells to change into cancer cells
oncogene: A gene that normally directs cell growth, but when altered, can promote cancer These genes are normally found in all cells, but oncogenes may undergo changes that activate them, causing cells to grow too quickly and form tumors
oncogene: a gene that causes normal cells to change into cancerous tumor cells
oncogene: A gene, one or more forms of that is associated with cancer Many oncogenes are involved, directly or indirectly, in controlling the rate of cell growth
oncogene: a gene associated with the development of cancer
oncogene: Gene that can cause cancer. It is a sequence of DNA that has been altered or mutated from its original form, the proto-oncogene (see mutation). Proto-oncogenes promote the specialization and division of normal cells. A change in their genetic sequence can result in uncontrolled cell growth, ultimately causing the formation of a cancerous tumour. In humans, proto-oncogenes can be transformed into oncogenes in three ways: point mutation (alteration of a single nucleotide base pair), translocation (in which a segment of the chromosome breaks off and attaches to another chromosome), or amplification (increase in the number of copies of the proto-oncogene). Oncogenes were first discovered in certain retroviruses and were later identified as cancer-causing agents in many animals. See also J. Michael Bishop; Harold Varmus
oncogene: fragments of genetic material (DNA) that carry the potential to cause cancer (transform normal cells into malignant cells)
oncogene: One of a large number of tgenes that can help make a cell cancerous Typically, a mutant form of a normal gene (proto-oncogene) involved in the control of cell growth or division The viral form of an oncogene is usually referred to as 'v-onc'
oncogene: a gene which normally directs cell growth, but when it becomes mutated, it has the ability to transform a normal cell into a tumor cell through uncontrolled growth
oncogene: A gene that normally directs cell growth If altered, an oncogene can promote or allow the uncontrolled growth of cancer Alterations can be inherited or caused by an environmental exposure to carcinogens
oncogene: A gene whose expression causes formation of a tumor
oncogene: a gene (e g , p53) that facilitates the development of cancer by regulating cell growth, either by actively "turning on" abnormal cell growth or failing to "turn off" normal cell growth
oncogene: A gene that contributes to cancer formation when mutated or inappropriately expressed (See Cellular oncogene, Dominant oncogene, Immortalizing oncogene, Recessive oncogene )
oncogene: Any gene associated with cancer Oncogenes are derived by the mutation of proto-oncogenes, normal cellular genes involved in growth control
oncogene: A normal cell gene that can cause cancer when it is mutated or damaged
oncogene: {i} (Medical) mutated gene that may result in the onset of cancer in an animal or human
oncogene: A gene that is capable of causing the transformation of normal cells into cancer cells 1