histocompatibility

English - Turkish

Definition of histocompatibility in English Turkish dictionary

{i} doku uyuşması

{i} dokuların uyumu

Related Terms

major histocompatibility complex

MHC kompleksi

English - English

Definition of histocompatibility in English English dictionary

the toleration of grafts between genetically similar individuals

{i} (Medicine) quality of being histocompatible; degree to which two people are histocompatible; compatibility of tissues; condition of having antigenic resemblances so that tissues or cells being transplanted from the donor to the recipient are not rejected

A state of mutual tolerance between tissues that allows them to be grafted effectively see MAJOR HISTOCOMPATIBILITY COMPLEX

the extent to which individuals or their tissues are immunologically similar

- a term that reflects the similarity in the tissues of the donor and recipient This similarity will help reduce the chances of rejection of the transplanted kidney

condition in which the cells of one tissue can survive in the presence of cells of another tissue; "a successful graft or translplant requires a high degree of histocompatibility

The examination of human leukocyte antigens (HLA) in a patient, often referred to as "tissue typing" or "genetic matching " Tissue typing is routinely performed for all donors and recipients in kidney and pancreas transplantation to help match the donor with the most suitable recipients This helps to decrease the likelihood of "rejecting" the transplanted organ

Referring to the similarity of tissue between different individuals The level of histocompatibility describes how well the patient and donor are matched The major histocompatibility determinants are the human leukocyte antigens (HLA) HLA typing is performed between the potential marrow donor and the potential transplant recipient to determine how close a HLA match the two are The closer the match, the less the donated marrow and the patient's body will react against each other (See "GVHD ")

The ability of a host to tolerate a tissue graft

Related Terms

histocompatibility antigen

any of the human leukocyte antigens (HLAs) which are the determinants of histocompatibility

histocompatibility gene

any of the genes, responsible for histocompatibility, that encode polymorphic cell-surface proteins

histocompatibility antigen

Any of the genetically determined antigens on the surface of cell membranes that identify a cell as self or nonself and that determine whether a tissue graft will be accepted by an organ transplant recipient

histocompatibility antigen

Any of the genetically determined antigens on the surface of cell membranes that serve to identify a cell as self or nonself. These antigens determine whether a tissue graft will be accepted by an organ transplant recipient

major histocompatibility complex

A group of genes that code for cell-surface histocompatibility antigens and are the principle determinants of tissue type and transplant compatibility