Condition caused by a chromosomal deficiency, whereby the patients bear a certain resemblance to the Mongoloid race, such as a small head and tilted eyelids
Down's syn·drome in AM, usually use Down syndrome Down's syndrome is a disorder that some people are born with. People who have Down's syndrome have a flat forehead and sloping eyes and lower than average intelligence. Variant of Down syndrome. a condition that someone is born with, that stops them from developing in a normal way, both mentally and physically (J. H. L. Down (1828-96), English doctor)