The document covers the following family planning methods: combined oral contraceptives (COCs), combined injectable contraceptives (CICs), progestogen-only pills (POPs), depot medroxyprogesterone acetate (DMPA), norethisterone enantate (NET-EN), levonorgestrel implants, emergency contraceptive pills (ECPs), copper-bearing interuterine devices, levonorgestrel-releasing interuterine devices (LNG IUDs), fertility awareness-based methods, and sterilization.
This has led to the selection of 4-guanidinobenzoates with either acetamenophen or ethylparaben as the phenol moiety for clinical evaluation, because they are orders of magnitude more contraceptive than nonoxynol-9 and less irritating to the vagina.