Definition of cushing's syndrome in English English dictionary
Hyperadrenocorticism or hypercorticism, an endocrine disorder caused by high levels of cortisol in the blood
A syndrome caused by an increased production of ACTH from a tumor of the adrenal cortex or of the anterior lobe of the pituitary gland, or by excessive intake of glucocorticoids. It is characterized by obesity and weakening of the muscles
Disorder named for Harvey Williams Cushing, caused by adrenal cortex overactivity. If caused by a pituitary gland tumour, it is called Cushing disease. Symptoms include obesity of the trunk and face ("moon face"), muscle wasting, high blood pressure, easy bruising, osteoporosis, diabetes mellitus, and fat between the shoulders ("buffalo hump"). Excess glucocorticoid hormones, whether produced by the adrenal gland or given as drugs, cause the symptoms, which are treated by surgery, radiation, cortisol-blocking drugs, or ending of glucocorticoid treatment. Cortisol treatment may be necessary after surgery