addison's disease

English - Turkish

Definition of addison's disease in English Turkish dictionary

Adison hastalığı

(Tıp) Adrenal kortekste yapılan kortizon ve aldosteron hormonlarının, yetersiz salgılanması

Related Terms

addison disease

Addison hastalığı

English - English

Definition of addison's disease in English English dictionary

a disorder in which the adrenal glands fail to produce a sufficient quantity of steroids, causing a brownish discoloration of the skin

Nearly thirty years before the date of Addison's discovery, his eminent colleague, Dr. Bright, had observed and recorded, in his celebrated 'Reports of Medical Cases,' a case of Addison's disease.

a glandular disorder caused by failure of function of the cortex of the adrenal gland and marked by anemia and prostration with brownish skin

bronze disease

Related Terms

Addison disease

Disease in which gradual atrophy of the adrenal cortex causes the adrenal glands to produce insufficient quantities of the steroid hydrocortisone while causing the pituitary gland to produce excess quantities of pituitary hormones. Most of the cortex tissue is destroyed by the time symptoms (including weakness, abnormal coloration, weight loss, and hypotension) appear. Hydrocortisone-replacement therapy is often successful, usually given with other hormones to stabilize sodium levels. More than half of cases are believed to be due to an autoimmune reaction (see autoimmune disease); the remainder are caused by destruction of the adrenal gland by granuloma (e.g., tuberculosis)

Hyphenation

addison's dis·ease

Turkish pronunciation

ädîsınz dîziz

Synonyms

chronic adrenal insufficiency, hypocorticism, hypocortisolism

Pronunciation

/ˈadəsənz dəˈzēz/ /ˈædɪsənz dɪˈziːz/

Etymology

() Named from Thomas Addison (1793-1860), M. D., of London, who first described it.