dis·ori·ent disorients disorienting disoriented in BRIT, also use disorientate If something disorients you, you lose your sense of direction, or you generally feel lost and uncertain, for example because you are in an unfamiliar environment. An overnight stay at a friend's house disorients me = confuse + disoriented dis·ori·ent·ed I feel dizzy and disoriented. + disorienting dis·ori·ent·ing An abrupt change of location can be disorienting. + disorientation dis·ori·en·ta·tion Morris was so stunned by this that he experienced a moment of total disorientation