ligand

listen to the pronunciation of ligand
Englisch - Türkisch
Biyokimyada bir ligand (Latince ligare = bağlanmak) bir biyomoleküle bağlanarak bir kompleks oluşturan bir bileşiktir. Genelde, iyonik bağlar, hidrojen bağları veya Van der Waals güçleri ile hedef bir proteindeki bağlanma yerine bağlanır. Ligand molekülün bağlanma yerine yanaşması genelde tersinir, yani birleşme ve ayrışma arasında bir denge vardır. Biyolojik sistemlerde bir ligandın hedef molekülü ile tersinmez kovalent bağlanması enderdir. İnorganik kimyadaki ligand tanımından farklı olarak, (hemoglobinde olduğu gibi) ligandın mutlaka bir metale bağlanması şart değildir. Sinyal reseptörlerine bir ligand bağlanınca reseptör proteinin üç boyutlu şekli değişebilir, bu da onun işlevsel özelliğini değiştirir. Bağlanma eğilimi veya gücüne "afinite" denir. Ligand tipleri arasında substratlar, inhibitörler, aktivatörler, ve nörotrasnmitterler sayılabilir. Radyoligandlar, radyoizotopla işaretlenmiş bileşiklerdir, ligand bağlanma ölçümlerinde kullanılırlar

Relevante Übersetzungen

ligands
ligandlar
bridging ligand
(Kimya) köprü ligant
spectator ligand
(Kimya) seyirci ligant
Englisch - Englisch
An ion, molecule, or functional group that binds to another chemical entity to form a larger complex
A Lewis base that can coordinate to a metal atom
(Chemistry) An ion or molecule attached to a metal atom by coordinate bonding
(Biochemistry) A molecule that selectively binds to another
A molecule that binds to a receptor protein
A Lewis base in a coordination compound
any molecule that binds to another
Molecule, ion, or group bound to the central atom in a chelate or a coordination compound
a molecule or ion that binds to a metal atom or ion through coordination of its lone electron pairs A coordination complex is formed when a metal ion is surrounded by a group of ligands
Any chemical that binds to a receptor Ligands may be agonists or antagonists
The binding agent used in affinity chromatography A ligand is bound to a column of a nonadsorbent material and selectively binds a substance in solution, isolating it from impurities Commonly used ligands include enzymes (for binding to inhibitors) or antibodies (for binding to antigens)
= Date: 1949: noun: a group, ion, or molecule coordinated to a central atom or molecule in a complex
A small molecule that binds to another larger molecule
A ligand is a substance which is capable of binding specifically and reversibly with a binder A ligand is termed an antigen when the binder is an antibody
Any molecule that binds to the surface of another molecule, such as an immune cell receptor For examples of receptors see CCR5, CXCR-4, CD4
A Lewis base coordinated with a metal atom or ion to form a coordination complex
A ligand is any chemical which binds to, forms a chemical link with, some larger molecule or receptor On cells the binding is to the outer part of the cell surface If a ligand can bind to two sites at once, it is called a divalent ligand, if three, trivalent, and if many sites can be attacked at once polyvalent
= molecule which binds to a receptor to form a complex
A molecule which binds to a receptor molecule, producing a response (closing an ion channel, transmitting a signal inside the cell etc )
Atom, group (see functional group), or molecule attached to a central atom, usually of a transition element, in a coordination or complex compound (see bonding). It is almost always the electron-pair donor (nucleophile) in a covalent bond. Common ligands include the neutral molecules water (H2O), ammonia (NH3), and carbon monoxide (CO) and the anions cyanide (CN^-), chloride (Cl^-), and hydroxide (OH^-). Rarely, ligands are cations and electron-pair acceptors (electrophiles). Organic ligands include EDTA (see chelate) and nitrilotriacetic acid. Biological systems rely on ligands such as the porphyrin in hemoglobin and chlorophyll, and numerous cofactors are ligands. In chelates, the ligand attaches at more than one point, sharing more than one electron pair, and is called bidentate or polydentate having two or many "teeth." The ligands in a complex may be the same or different
an atom or molecule or radical or ion that forms a complex around a central atom
A molecule that can bind to a receptor and thereby induce a signal in the cell, e g , a hormone
The ion or molecule which surrounds or complexes with the central atom or ion
A molecule that reacts to form a complex with another molecule
Molecule that binds to a specific site on a protein or another molecule
A small molecule that binds to a receptor/protein
an ion or neutral molecule attached to the central metal ion in a coordination compound
A chemical which binds to a receptor
a molecule that binds to a specific receptor
In °protein chemistry, a small molecule that is (or can be) bound by a larger molecule is termed a ligand In organometallic chemistry, a moiety bonded to a central metal atom is also termed a ligand; the latter definition is more common in general chemistry

Relevante Übersetzungen

ligand field theory
a theory, a combination of the earlier crystal field theory with molecular orbital theory, that describes the structure of coordination compounds
backbonding ligand
A ligand that has two or more bonds to the same metal centre
bridging ligand
A ligand which is bound to more than one metal centre
pentadentate ligand
(Kimya) A chelating agent having five groups capable of attachment to a metal ion. Also known as quinquidentate ligand
ligands
The molecules surrounding a metal ion in a complex ion See Chelate and Complexation
ligands
Biological agents (usually chemicals, proteins or antibodies) that bind to receptors (proteins or DNA)
ligands
molecules, either synthetic or of natural origin, that are able to specifically bind certain proteins In the case of natural ligands, such as hormones, the proteins they bind are called receptors
ligands
plural of ligand
ligand

    Silbentrennung

    lig·and

    Türkische aussprache

    lîgınd

    Aussprache

    /ˈləgənd/ /ˈlɪɡənd/

    Etymologie

    () From Latin ligandus, gerundive of ligare ‘to bind’.
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