{i} large aerial bomb; hugely successful hit, something that is very popular (movie, book, etc.); hit, movie which is a gigantic financial success; person or thing which is very impressive; real estate agent who practices blockbusting
A blockbuster is a film or book that is very popular and successful, usually because it is very exciting. a book or film that is very good or successful
an unsually successful hit with widespread popularity and huge sales (especially a movie or play or recording or novel)
an unsually successful hit with widespread popularity and huge sales (especially a movie or play or recording or novel) a large bomb used to demolish extensive areas (as a city block)
A blockbuster drug is a drug generating more than $1 billion of revenue for its owner each year. The search for blockbusters has been the foundation of the R&D strategy adopted by big pharmaceutical companies, but this looks set to change. New advances in genomics, and the promise of personalized medicine, are likely to fragment the pharmaceutical market