The process by which tumor cells are removed from the marrow or blood stem cell suspension that are to be used for an autologous transplant The stem cells used in an autologous transplant are obtained from a patient with leukemia, lymphoma, or myeloma The patient is usually treated to induce a remission before the stem cells are harvested but some inapparent tumor cells are probably always present Purging is used to try to minimize the chance of returning tumor cells to the patient with the stem cells infusion after intensive and hopefully curative cytotoxic treatment is given
process by which certain types of cells are removed from bone marrow prior to infusion into the BMT patient In autologous BMTs, marrow may be purged to remove lingering cancerous cells In allogeneic BMTs, donor bone marrow may be purged to remove cells that cause graft-versus-host disease
The process of supplying an enclosure with a protective gas at a sufficient flow and positive pressure to reduce the concentration of any flammable gas or vapor initially present to an acceptable level
The removal of classified or sensitive data from a storage medium in such a way that there is assurance, proportional to the sensitivity of the data, that the data may not be reconstructed using laboratory techniques