crossover trial teriminin İngilizce İngilizce sözlükte anlamı
In crossover trials, each subject receives at least two different treatments In general, one group receives treatment A while the other receives treatment B At some point in the study, each group then crosses over to the other treatment
(Cochrane definition) A type of clinical trial comparing two or more interventions in which the participants, upon completion of the course of one treatment, are switched to another For example, for a comparison of treatments A and B, half the participants are randomly allocated to receive them in the order A, B and half to receive them in the order B, A A problem with this study design is that the effects of the first treatment may carry over into the period when the second is given
in crossover trials, each subject receives both treatments being compared (often the test drug for one period and the placebo for another period) Such trials are used for patients who have a stable, usually chronic, condition during both treatment period