sickle cell anemia

الإنجليزية - التركية

تعريف sickle cell anemia في الإنجليزية التركية القاموس.

orak hücre anemisi

orak hücreli anemi

الإنجليزية - الإنجليزية

تعريف sickle cell anemia في الإنجليزية الإنجليزية القاموس.

(Medicine) hereditary disease characterized by anemia resulting from defective hemoglobin production (causes deformed red blood cells, oxygen deficiency, and circulatory problems)

A chronic, usually fatal anemia marked by sickle-shaped red blood cells, occurring almost exclusively in Black people of Africa or of African descent, and characterized by episodic pain in the joints, fever, leg ulcers, and jaundice. The disease occurs in individuals who are homozygous for a mutant hemoglobin gene. Also called sickle cell disease

A disease characterized by sickle-shaped red blood cells

a congenital form of anemia occurring mostly in blacks; characterized by abnormal blood cells having a crescent shape

Blood disorder (see hemoglobinopathy) seen mainly in persons of Sub-Saharan African ancestry and their descendants and in those from the Middle East, the Mediterranean area, and India. About 1 in 400 blacks worldwide has the disease, caused by inheriting two copies of a recessive gene that makes those with one copy (about 1 in 12 blacks worldwide) resistant to malaria. The gene specifies a variant hemoglobin (hemoglobin S or Hb S) that distorts red blood cells (erythrocytes) into a rigid sickle shape. The cells become clogged in capillaries, damaging or destroying various tissues. Symptoms include chronic anemia, shortness of breath, fever, and episodic "crises" (severe pain in the abdomen, bones, or muscles). Hydroxyurea treatment triggers production of fetal hemoglobin (Hb F), which does not sickle, greatly lessening severity of crises and increasing life expectancy, previously about 45 years

الواصلة

sick·le cell a·ne·mi·a

التركية النطق

sîkıl sel ınimiı

النطق

/ˈsəkəl ˈsel əˈnēmēə/ /ˈsɪkəl ˈsɛl əˈniːmiːə/