The process, in the regulation of gene expression, in which the number, or activity of receptors decreases in order to decrease sensitivity
(Tıp, İlaç) Downregulation is the process by which a cell decreases the number of a cellular component, such as RNA or protein in response to external variable. A increase of component is called upregulation. For example, the cell decreases the number of receptors to a given hormone or neurotransmitter to reduce its sensitivity to this molecule
Downregulation is the process by which a cell decreases the number of a cellular component, such as RNA or protein in response to external variable. A increase of component is called upregulation