anaplasia

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anaplastic
anaplastik
İngilizce - İngilizce
A reversion of differentiation in cells that is characteristic of malignancy in tumours
{i} loss of structural differentiation of unique features inside a cell or group of cells; dedifferentiation
Replacement of specialized cells by unspecialized, undifferentiated, or stem cells; dedifferentiation
lack of differentiation manifested as abnormal architectural and cytologic features Characteristic cytologic features include nuclear and cellular pleomorphism (variation in size and shape), nuclear hyperchromatism (dark staining), the presence of tumor giant cells (abnormal large cells with lobated, polyploid nuclei), and abnormal mitoses (tripolar or quadripolar nuclear spindles) Characteristic architectural abnormalities include loss of normal orientation of the cells within the tissue both in their relationship to the underlying stroma and to adjacent cells
In the case of a body cell, a reversion to a more primitive condition A term used to denote the alteration in cell character which constitutes malignancy
The loss of structural organization and useful function of a cell
characteristics of a cell identifies it as a cancer cell Malignant
loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumor
anaplastic
Of, or relating to, a tumor that shows little histogenetic differentiation. It implies that a tumor is high grade and likely to behave in an aggressive fashion
Anaplastic
of or relating to anaplasia
anaplastic
Of or pertaining to anaplasty
anaplastic
{s} replacing or repairing tissues (Surgical); extremely malignant (referring to tumors)
anaplasia