anaplasia teriminin İngilizce İngilizce sözlükte anlamı
A reversion of differentiation in cells that is characteristic of malignancy in tumours
{i} loss of structural differentiation of unique features inside a cell or group of cells; dedifferentiation
Replacement of specialized cells by unspecialized, undifferentiated, or stem cells; dedifferentiation
lack of differentiation manifested as abnormal architectural and cytologic features Characteristic cytologic features include nuclear and cellular pleomorphism (variation in size and shape), nuclear hyperchromatism (dark staining), the presence of tumor giant cells (abnormal large cells with lobated, polyploid nuclei), and abnormal mitoses (tripolar or quadripolar nuclear spindles) Characteristic architectural abnormalities include loss of normal orientation of the cells within the tissue both in their relationship to the underlying stroma and to adjacent cells
In the case of a body cell, a reversion to a more primitive condition A term used to denote the alteration in cell character which constitutes malignancy
Of, or relating to, a tumor that shows little histogenetic differentiation. It implies that a tumor is high grade and likely to behave in an aggressive fashion