a disorder in which the adrenal glands fail to produce a sufficient quantity of steroids, causing a brownish discoloration of the skin
Nearly thirty years before the date of Addison's discovery, his eminent colleague, Dr. Bright, had observed and recorded, in his celebrated 'Reports of Medical Cases,' a case of Addison's disease.
Disease in which gradual atrophy of the adrenal cortex causes the adrenal glands to produce insufficient quantities of the steroid hydrocortisone while causing the pituitary gland to produce excess quantities of pituitary hormones. Most of the cortex tissue is destroyed by the time symptoms (including weakness, abnormal coloration, weight loss, and hypotension) appear. Hydrocortisone-replacement therapy is often successful, usually given with other hormones to stabilize sodium levels. More than half of cases are believed to be due to an autoimmune reaction (see autoimmune disease); the remainder are caused by destruction of the adrenal gland by granuloma (e.g., tuberculosis)
an English writer who wrote articles for The Tatler and The Spectator (1672-1719). born May 1, 1672, Milston, Wiltshire, Eng. died June 17, 1719, London English essayist, poet, and dramatist. His poem on the Battle of Blenheim, The Campaign (1705), brought him to the attention of leading Whigs and paved the way to important government posts (including secretary of state) and literary fame. With Richard Steele, he was a leading contributor to and guiding spirit of the periodicals The Tatler (1709-11) and The Spectator (1711-12, 1714). One of the most admired masters of English prose, he brought to perfection the periodical essay. His Cato (1713), a highly successful play with political overtones, is one of the important tragedies of the 18th century
addison
Heceleme
Ad·di·son
Türkçe nasıl söylenir
ädısın
Telaffuz
/ˈadəsən/ /ˈædəsən/
Etimoloji
() A patronymic surname "son of Adam" from a medieval diminutive form.